Combinatorial gene therapy renders increased survival in cirrhotic rats
نویسندگان
چکیده
منابع مشابه
Increased survival of cirrhotic patients with septic shock
INTRODUCTION The overall outcome of septic shock has been recently improved. We sought to determine whether this survival gain extends to the high-risk subgroup of patients with cirrhosis. METHODS Cirrhotic patients with septic shock admitted to a medical intensive care unit (ICU) during two consecutive periods (1997-2004 and 2005-2010) were retrospectively studied. RESULTS Forty-seven and ...
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متن کاملIncreased cytochrome oxidase activity in adrenal glands of thioacetamide-cirrhotic rats.
OBJECTIVES Cytochrome oxidase activity has been determined in the adrenal glands of thioacetamide (TAA)-cirrhotic rats. MATERIAL AND METHODS Two groups of animals (Control group; n=10 and TAA group; n=11) of three months evolution were used to study the cytochrome oxidase activity in the suprarenal cortex (glomerular, fascicular and reticular layers) and medulla. TAA was administered orally a...
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BACKGROUND AND AIMS Anandamide is an endocannabinoid that evokes hypotension by interaction with peripheral cannabinoid CB1 receptors and with the perivascular transient receptor potential vanilloid type 1 protein (TRPV1). As anandamide has been implicated in the vasodilated state in advanced cirrhosis, the study investigated whether the mesenteric bed from cirrhotic rats has an altered and sel...
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In a cirrhotic liver, regenerative ability is so impaired that massive resection easily complicates postoperative liver dysfunction, which frequently leads to life-threatening multiple-organ failure. Transforming growth factor-beta1 (TGF-beta1) is considered to be a key cytokine regulating both hepatocyte proliferation and matrix expression in fibrosis. Therefore, we investigated the effect of ...
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ژورنال
عنوان ژورنال: Journal of Biomedical Science
سال: 2010
ISSN: 1423-0127
DOI: 10.1186/1423-0127-17-42